Workshop Title:

Patient- and Tissue-Specific Approaches in Implantable Biomaterial Design, Development and Production

Date:

August 23rd, 2024 (GMT+3)

Organizer:

Biomedical Engineering Department, Engineering and Architecture Faculty, Eskişehir Osmangazi University

Keywords:

• Biomaterials
• Implant Design
• 3D-Printing
• Mechanical Characterization
• Electrochemical Characterization
• Tissue Compatibility
• Cell Culture

Workshop Chair:

Personal Bio:

Omer Burak Istanbullu is an Assistant Professor and department vice chair of Biomedical Engineering Department at Eskisehir Osmangazi University. After studying in the field of biomedical engineering and specializing on tumor segmentation from magnetic resonance images at Erciyes University, he then pursued a Master's program at Istanbul Technical University and Erciyes University with the scope of biomaterial-medical imaging device compatibility. Following the Master's degree, he received a Ph.D. from Erciyes University, in the field of biocompatibility improvement of implantable intravascular biomaterials using biomimetic surface modification approaches. Dr. Istanbullu is experienced in the development and improvement of biocompatible materials using biomimetic approaches, combining the computational methods and experimental analysis to achieve the most effective solutions for the challenges related to biomaterials. His research interests include surface modification by biomimetic approaches, diamond-like carbon and carbon nanotubes, electrochemical, thermal and mechanical characterization of biomaterials, anticorrosive and biocompatible surface development. The overall goal of Dr. Istanbullu through his work is contributing to the development of new and innovative biomaterials that have the potential to reduce the biomaterial-based risks in the field of biomedical engineering.

Workshop Description:

Background:

The design of implantable biomaterials plays a crucial role in the success of surgical intervention applications. In the context of implant production, factors such as implant geometry and shape, surface characteristics, and mechanical behavior alongside the material selection, significantly impact on tissue-integration and biocompatibility. Therefore, improvement in such properties directly contribute in the treatment success and durability of both permanent and biodegradable implants. The implants must address diverse requirements arising from the varying anatomical structures of individual patients and the characteristics of different tissues within the human body. Thereby, biomaterial and implant designs need to be tailored to be patient- and tissue- specific to ensure optimal performance. This customization is particularly crucial in orthopedic applications where varying features are expected from the implants which interact with lower or upper extremity bones, especially for load-bearing applications. Thus, the mechanical features and surface properties of implants should be aligned with the anticipated behavior of the target patient's anatomy and the specific target tissue. In light of these considerations, each implantable biomaterial necessitates a comprehensive design, development, and production process that takes into account the mechanical, biological, and chemical aspects of the target tissue and anatomy.

Goal/Rationale:

The workshop aims to address the effects of biomaterial design on mechanical and biological behavior of the implants. The content lies in understanding and optimizing the collective impact of implant geometry, shape, surface characteristics, and mechanical behavior on tissue compatibility. The necessity for customization, particularly in orthopedic applications with load-bearing implants, adds intricacies due to diverse patient anatomies and tissue characteristics. Recent advances including the application of advanced manufacturing techniques such as 3D printing, 3D bioprinting, 4D printing, and micro/nano-scale engineering, offer precise customization and bridging over the implant design and production. Furthermore, biomimetic approaches, inspired by natural biological structures, contribute to improved tissue-compatibility in physical, chemical and biological manner. The workshop has three key objectives: first, to comprehensively understand the interactions of implant properties with target tissues; second, to explore strategies for tailoring biomaterial and implant designs to be patient- and tissue-specific by both theoretical and experimental approaches; and third, to showcase recent advances and innovations in biomaterial design, emphasizing breakthroughs in biomedical and materials science, tissue engineering, and nanotechnology. Thus, the workshop serves as a platform for researchers and practitioners to exchange knowledge and insights, fostering collaboration and propelling the field of implantable biomaterials towards new frontiers.

Scope and Information for Participants:

The workshop invites researchers, academics, practitioners, and professionals in the fields of biomedical engineering, bioengineering, materials science, and chemical engineering to participate. This workshop covers the topics of biomaterials design, development and production, mechanical and electrochemical characterization, surface modification and functional enhancement considering target-tissue specifications and target-patient features. The topics will be addressed by both finite element-based and experimental analysis including mechanical tests, cell and culture applications, and electrochemical corrosion behavior analysis. Molecular dynamic simulation studies and practical approaches in the analysis of the implants under various conditions are also welcomed in this workshop. Attendees will have the opportunity to engage in discussions, network with peers, and learn about cutting-edge computational modelling techniques and applications in biomaterials.

Venue:

Büyükdere Meşelik Yerleşkesi, 26040 Odunpazarı/Eskişehir, Turkey

VISA:

(www.mfa.gov.tr)

Visitors who are not exempt from entry visa must obtain their visas or schedule an appointment with the Turkish Consular offices via Pre-Application System for Turkish Sticker Visa (www.visa.gov.tr). The applicants who meet the requirements will be directed by the Pre-Application System for Turkish Sticker Visa to the e-Visa system (www.evisa.gov.tr) In those countries where Türkiye does not have a consular representation can also use online scheduling for appointments with the nearest accredited consular office of Türkiye.

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Attend in person:

If you want to attend the workshop on-site, please email the Conference Committee: [email protected].